منابع مشابه
Amisulpride, an unusual "atypical" antipsychotic: a meta-analysis of randomized controlled trials.
OBJECTIVE The "atypical" profile of the new antipsychotics clozapine, olanzapine, quetiapine, and risperidone has been linked to combined antagonism of serotonin 2 (5-HT(2)) and dopamine 2 (D(2)) receptors. Although amisulpride is a highly selective D(3)/D(2) receptor antagonist, it is assumed to have atypical properties as well. The purpose of this article was to compare the atypical profile o...
متن کاملPsychopharmacological profile of amisulpride: an antipsychotic drug with presynaptic D2/D3 dopamine receptor antagonist activity and limbic selectivity.
Amisulpride, a benzamide derivative, is an antipsychotic drug with a pharmacological profile distinct from that of classical neuroleptics such as haloperidol and from that of another benzamide, remoxipride. In mice, amisulpride antagonized hypothermia induced by apomorphine, quinpirole or (+/-) 7-hydroxy-2-(di-n-propylamino)-tetralin, an effect involving D2/D3 receptors, at similar doses (ED50 ...
متن کاملHyperprolactinaemia with amisulpride.
Psychopharmaca are used in treatment of psychiatric illnesses and disorders, among other therapeutic possibilities. The choice of the psychopharmaca is determined by the specific psychopathology of the patient, within the diagnostic categories, according to the current classification of diseases and disorders. With the advances in pharmaco industry, the range of drugs used in the everyday clini...
متن کاملClozapine augmentation with amisulpride.
A 42-year-old man with treatmentresistant schizophrenia presented a progressive clinical worsening under clozapine treatment (450 mg/d). He experienced worsening auditory hallucinations, increased distress and decreased working and social functioning (Positive and Negative Syndrome Scale [PANSS] score 97; positive subscale 21; negative subscale 31; general subscale 45). He experienced several s...
متن کاملD2 receptor occupancy during high- and low-dose therapy with the atypical antipsychotic amisulpride: a 123I-iodobenzamide SPECT study.
UNLABELLED Amisulpride appears to be an effective agent for treating positive or negative symptoms of schizophrenia, depending on dose. The aim of this study was to assess striatal dopamine D(2) receptor availability by means of (123)I-iodobenzamide (IBZM) SPECT in patients treated with high and low doses of this atypical antipsychotic drug. METHODS Twenty-nine patients (19 men and 10 women, ...
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ژورنال
عنوان ژورنال: Acta Medica Marisiensis
سال: 2015
ISSN: 2247-6113
DOI: 10.1515/amma-2015-0072